Experimental Biology and Medicine | Genomics, Proteomics and Bioinformatics

Original Research

Published on 17 Jul 2025

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

in Genomics, Proteomics and Bioinformatics

Eleonora Sabetta
Karin Rallmann
Jonas Bergquist
Pille Taba
Abigail L. Pfaff
Bal Hari Poudel
Davide Ferrari
Massimo Locatelli
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10593

2,667 views

Original Research

Published on 11 Jul 2025

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

in Genomics, Proteomics and Bioinformatics

Li-Li Zhang
Zhe Wang
Ying Zhou
Dai-Yang Li
Xiao-Nian Tu
Yu-Xia Li
Ke-Ming Du
Zhong-Zheng Zheng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10128

1,565 views

Original Research

Published on 03 Jun 2025

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10575

1,991 views
8 citations

Original Research

Published on 29 May 2025

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Vivien J. Bubb
John P. Quinn
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10600

2,219 views
2 citations

Original Research

Published on 30 Apr 2025

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

in Genomics, Proteomics and Bioinformatics

Yan Zhang
Honggang Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10469

1,901 views
1 citation

Original Research

Published on 15 Jan 2025

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

in Genomics, Proteomics and Bioinformatics

Landi Su
Jingjing Li
Li Qin
Yang Feng
Dingwen Xu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10281

1,773 views

Original Research

Published on 08 Jan 2025

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

in Genomics, Proteomics and Bioinformatics

Sulev Kõks
Karin Rallmann
Mari Muldmaa
Jack Price
Abigail L. Pfaff
Pille Taba

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10401

2,389 views
17 citations

Original Research

Published on 23 Sep 2024

Integrated multi-omics profiling reveals the ZZZ3/CD70 axis is a super-enhancer-driven regulator of diffuse large B-cell lymphoma cell-natural killer cell interactions

in Genomics, Proteomics and Bioinformatics

Xi Li
Juya Cui
Liao Wang
Caihong Cao
Hu Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10155

3,977 views

Correction

Published on 19 Sep 2024

Corrigendum: Genome-wide association study identifying variants related to performance and injury in high-performance athletes

in Genomics, Proteomics and Bioinformatics

Jay R. Ebert
Agnes Magi
Eve Unt
Ele Prans
David J. Wood
Sulev Koks

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10348

1,310 views
1 citation

Review

Published on 18 Sep 2024

Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells

in Genomics, Proteomics and Bioinformatics

Wen-Bin Liu
Damian Fermin
An-Long Xu
Jeffrey B. Kopp
Qihe Xu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10167

5,771 views
3 citations

Original Research

Published on 22 Jul 2024

The causal relationship between autoimmune diseases and rhinosinusitis, and the mediating role of inflammatory proteins: a Mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Yanjing Liang
Shao Yin
Xiangyan Chen
Chengen Li
Qiu Chen

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10196

3,485 views
11 citations

Original Research

Published on 09 Jul 2024

Identification of potential biomarkers for cerebral palsy and the development of prediction models

in Genomics, Proteomics and Bioinformatics

Haoyang Zheng
Duo Zhang
Yong Gan
Zesheng Peng
Yuyi Wu
Wei Xiang

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10101

2,894 views
4 citations

Original Research

Published on 27 Jun 2024

Bioinformatics and systems biology approach to identify the pathogenetic link of neurological pain and major depressive disorder

in Genomics, Proteomics and Bioinformatics

Jinjing Hu
Jia Fu
Yuxin Cai
Shuping Chen
Mengjian Qu
Lisha Zhang
Weichao Fan
Ziyi Wang
Qing Zeng
Jihua Zou

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10129

3,293 views
2 citations

Original Research

Published on 20 Jun 2024

The whole transcriptome analysis using FFPE and fresh tissue samples identifies the molecular fingerprint of osteosarcoma

in Genomics, Proteomics and Bioinformatics

Bal Hari Poudel
Sulev Koks

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10161

3,138 views
27 citations

Original Research

Published on 18 Mar 2024

Transcriptional-profile changes in the medial geniculate body after noise-induced tinnitus

in Genomics, Proteomics and Bioinformatics

Peng Liu
Xinmiao Xue
Chi Zhang
Hanwen Zhou
Zhiwei Ding
Li Wang
Yuke Jiang
Wei-Dong Shen
Shiming Yang
Fangyuan Wang

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10057

3,285 views
3 citations

Original Research

Published on 29 Feb 2024

Weighted gene co-expression network analysis reveals immune evasion related genes in Echinococcus granulosus sensu stricto

in Genomics, Proteomics and Bioinformatics

Ismael Pereira
Gabriela Prado Paludo
Christian Hidalgo
Caroll Stoore
María Soledad Baquedano
Carolina Cabezas
Martín Cancela
Henrique Bunselmeyer Ferreira
Macarena Bastías
Aníbal Riveros

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10126

2,494 views
2 citations

40 articles

articles

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

Integrated multi-omics profiling reveals the ZZZ3/CD70 axis is a super-enhancer-driven regulator of diffuse large B-cell lymphoma cell-natural killer cell interactions

Corrigendum: Genome-wide association study identifying variants related to performance and injury in high-performance athletes

Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells

The causal relationship between autoimmune diseases and rhinosinusitis, and the mediating role of inflammatory proteins: a Mendelian randomization study

Identification of potential biomarkers for cerebral palsy and the development of prediction models

Bioinformatics and systems biology approach to identify the pathogenetic link of neurological pain and major depressive disorder

The whole transcriptome analysis using FFPE and fresh tissue samples identifies the molecular fingerprint of osteosarcoma

Transcriptional-profile changes in the medial geniculate body after noise-induced tinnitus

Weighted gene co-expression network analysis reveals immune evasion related genes in Echinococcus granulosus sensu stricto